Ru-catalyzed tandem cross-metathesis/intramolecular-hydroarylation sequence

被引：115

作者：

Chen, Jia-Rong ^{[1
]}

Li, Chang-Feng ^{[1
]}

An, Xiao-Lei ^{[1
]}

Zhang, Ji-Ji ^{[1
]}

Zhu, Xiao-Yu ^{[1
]}

Xiao, Wen-Jing ^{[1
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 13期

关键词：

cross-metathesis; homogeneous catalysis; hydroarylation; ruthenium; tandem reactions;

D O I：

10.1002/anie.200705194

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

(Chemical Equation Presented) Sometimes it only takes one to tango: A novel ruthenium-catalyzed tandem cross-metathesis/intramolecular-hydroarylation reaction of alkenyl indoles has been developed which relies on a single catalyst for the tandem sequence and provides an efficient synthesis of fused polycyclic indole compounds with good to excellent overall yields (see scheme; Ts = 4-toluenesulfonyl, DCE = 1,2-dichloroethane, Mes = 2,4,6-Me3C 6H2). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2489 / 2492

页数：4

共 58 条

[1]

New versatile route to the synthesis of tetrahydro-β-carbolines and tetrahydro-pyrano[3,4-b]indoles via an intramolecular Michael addition catalyzed by InBr3 [J].