Potential applications of violacein: a microbial pigment

被引:84
作者
Duran, Marcela [1 ,2 ]
Ponezi, Alexandre N. [3 ]
Faljoni-Alario, Adelaide [4 ]
Teixeira, Maria F. S. [5 ]
Justo, Giselle Z. [6 ,7 ]
Duran, Nelson [1 ,2 ]
机构
[1] Univ Estadual Campinas UNICAMP, Inst Chem, Biol Chem Lab, BR-13083970 Campinas, SP, Brazil
[2] Univ Fed ABC, Ctr Nat & Human Sci, Dept Biochem & Biophys, BR-09210170 Santo Andre, SP, Brazil
[3] Univ Estadual Campinas, Pluridisciplinary Ctr Chem Biol & Agr Res CPQBA, Div Microbiol, Campinas, SP, Brazil
[4] Univ Fed ABC UFABC, Ctr Nat & Human Sci, Dept Biochem & Biophys, BR-09210170 Santo Andre, SP, Brazil
[5] Univ Fed Amazonas UFAM, Mycol Lab, BR-69000070 Manaus, Amazonas, Brazil
[6] Univ Fed Sao Paulo UNIFESP, Dept Biol Sci, BR-04044020 Sao Paulo, Brazil
[7] Univ Fed Sao Paulo UNIFESP, Dept Biochem, BR-04044020 Sao Paulo, Brazil
基金
巴西圣保罗研究基金会;
关键词
Violacein; Chromobacterium violaceum; Cosmetics; Textile; Therapy; CHROMOBACTERIUM-VIOLACEUM; VIOLET PIGMENT; PSYCHROTROPHIC BACTERIUM; INCLUSION COMPLEX; CYTOTOXICITY; APOPTOSIS; NANOPARTICLES; EXPRESSION; CHEMISTRY; MECHANISM;
D O I
10.1007/s00044-011-9654-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Violacein is a versatile pigment from a bacterium Chromobacterium violaceum that exhibits several biological activities and, at present, has gained increasing importance in industrial markets, such as in medicine, cosmetics, and textiles. In this mini-review, we aimed to describe violacein production and to explore its various biological properties in a pharmacological context, including its antioxidant, immunomodulatory, antitumoral, and antiparasitic activities. In addition, its use in the fields of cosmetics, textiles, food, toys, and insecticides has emerged as unusual potential areas of application to be discussed here.
引用
收藏
页码:1524 / 1532
页数:9
相关论文
共 74 条
[1]   Stable high level expression of the violacein indolocarbazole anti-tumour gene cluster and the Streptomyces lividans amyA gene in E. coli K12 [J].
Ahmetagic, Adnan ;
Pemberton, John M. .
PLASMID, 2010, 63 (02) :79-85
[2]  
Alves OL, 2005, Brazilian Patent, Patent No. [05026571, PIBr 0502657-1]
[3]   Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum [J].
Andrighetti-Fröhner, CR ;
Antonio, RV ;
Creczynski-Pasa, TB ;
Barardi, CRM ;
Simoes, CMO .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2003, 98 (06) :843-848
[4]   Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum [J].
Antonisamy, P. ;
Ignacimuthu, S. .
PHYTOMEDICINE, 2010, 17 (3-4) :300-304
[5]   Anti-diarrhoeal and ulcer-protective effects of violacein isolated from Chromobacterium violaceum in Wistar rats [J].
Antonisamy, Paulrayer ;
Kannan, Ponnusamy ;
Ignacimuthu, Savarimuthu .
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2009, 23 (04) :483-490
[6]  
Baek SH, 2007, Republic Korean Kongkae Taekho Kongbo, Patent No. [2007088150, KR 2007088150A]
[7]   Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor [J].
Bromberg, Natalia ;
Dreyfuss, Juliana L. ;
Regatieri, Caio V. ;
Palladino, Marcelly V. ;
Duran, Nelson ;
Nader, Helena B. ;
Haun, Marcela ;
Justo, Giselle Z. .
CHEMICO-BIOLOGICAL INTERACTIONS, 2010, 186 (01) :43-52
[8]   Investigating the antioxidant mechanism of violacein by density functional theory method [J].
Cao, Wei ;
Chen, Weijun ;
Sun, Shaofang ;
Guo, Ping ;
Song, Jirong ;
Tian, Chengrui .
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2007, 817 (1-3) :1-4
[9]  
Costa FTM, 2005, Brazilian Patent, Patent No. [PIBr 056399-0, 0563990]
[10]  
De Azevedo M.B.M., 2000, Proc. Intern. Symp. Control. Rel. Bioact. Mater, V27, P506