Protein design and phage display

被引：118

作者：

Hoess, RH ^{[1
]}

机构：

[1] Dupont Merck Pharmaceut Co, Expt Stn, Wilmington, DE 19880 USA

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 10期

关键词：

D O I：

10.1021/cr000056b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The techniques used for designing proteins were discussed. The large combinatorial libraries of encoded peptides or proteins were displayed as fusion to the phage capsid. It was shown that the phage display was an indispensable tool for protein engineering and effectively improves the binding properties of various proteins to ligands.

引用

页码：3205 / 3218

页数：14

共 116 条

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