Secreted Peptide Signals Required for Maintenance of Root Stem Cell Niche in Arabidopsis

被引：363

作者：

Matsuzaki, Yo ^{[1
]}

Ogawa-Ohnishi, Mari ^{[1
]}

Mori, Ayaka ^{[1
]}

Matsubayashi, Yoshikatsu ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Bioagr Sci, Chikusa Ku, Nagoya, Aichi 4648601, Japan

来源：

SCIENCE | 2010年 / 329卷 / 5995期

基金：

日本学术振兴会;

关键词：

PHYTOSULFOKINE; PROLIFERATION; PROTEINS; GENES;

D O I：

10.1126/science.1191132

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Stem cells are maintained in the niche by intercellular interactions and signaling networks. In this work, we study extracellular signals required for maintenance of the root stem cell niche in higher plants. We identify a family of functionally redundant homologous peptides that are secreted, tyrosine-sulfated, and expressed mainly in the stem cell area and the innermost layer of central columella cells. We name these peptides root meristem growth factors (RGFs). RGFs are required for maintenance of the root stem cell niche and transit amplifying cell proliferation in Arabidopsis. RGF1 defines expression levels and patterns of the stem cell transcription factor PLETHORA, mainly at the posttranscriptional level. The RGFs function independently of the auxin pathway. These peptide signals play a crucial role in postembryonic root development.

引用

页码：1065 / 1067

页数：3

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