The genetics of frontotemporal dementia

被引:9
作者
Haugarvoll, Kristoffer
Wszolek, ZbIgniew K.
Hutton, Michael
机构
[1] Mayo Clin, Coll Med, Dept Neurosci, Jacksonville, FL 32224 USA
[2] Mayo Clin, Coll Med, Dept Neurol, Jacksonville, FL 32224 USA
[3] Norwegian Univ Sci & Technol, NTNU, Dept Neurosci, N-7489 Trondheim, Norway
关键词
D O I
10.1016/j.ncl.2007.03.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This article describes the remarkable progress that has been made over the past decade in identifying the genetic contribution to frontotemporal dementia. The clinical and neuropathologic features of frontotemporal dementia with parkinsonism linked to chromosome 17 and the nature of the mutations in the progranulin and microtubule-associated protein tau genes are emphasized.
引用
收藏
页码:697 / +
页数:20
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