RuCl3 catalyzed one-pot synthesis of α-aminonitriles

被引：80

作者：

De, SK

机构：

[1] Dept. Med. Chem./Molec. Pharmacol., Purdue Cancer Center, Purdue University, West Lafayette

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 05期

关键词：

aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles; ruthenium trichloride;

D O I：

10.1081/SCC-200050347

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient method was developed for the synthesis of alpha-aminonitriles by simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of RuCl3 at room temperature.

引用

页码：653 / 656

页数：4

共 15 条

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