New Heck-type reaction applied to the synthesis of protoporphyrin-IX derivatives

被引：20

作者：

Castella, M

Calahorra, F

Sainz, D

Velasco, D

机构：

[1] Univ Barcelona, Dept Quim Organ, E-08028 Barcelona, Catalunya, Spain

[2] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Catalunya, Spain

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 04期

关键词：

D O I：

10.1021/ol000370s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new Heck type reaction under catalysis by Pd for obtaining polysubstituted arylvinylydene derivatives of porphyrin systems is reported. The coupling between the Zn(ll) protoporphyrin IX dimethylester Zn-2 and several bromo aryl and iodo aryl compounds in the presence of a new Pd catalyst has been studied. This coupling reaction, although providing moderate regioselectivity, gives quantitative conversion.

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页码：541 / 544

页数：4

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