Influenza a virus (H3N8) in dogs with respiratory disease, Florida

被引：148

作者：

Payungporn, Sunchai ^{[1
,4
]}

Crawford, P. Cynda ^{[2
]}

Kouo, Theodore S. ^{[1
]}

Chen, Li-mei ^{[1
]}

Pompey, Justine ^{[1
]}

Castleman, William L. ^{[2
]}

Dubovi, Edward J. ^{[3
]}

Katz, Jacqueline M. ^{[1
]}

Donis, Ruben O. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[2] Univ Florida, Gainesville, FL USA

[3] Cornell Univ, Ithaca, NY USA

[4] Chulalongkorn Univ, Fac Med, Dept Biochem, Bangkok 10330, Thailand

来源：

EMERGING INFECTIOUS DISEASES | 2008年 / 14卷 / 06期

关键词：

D O I：

10.3201/eid1406.071270

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2004, canine influenza virus subtype H3N8 emerged in greyhounds in the United States. Subsequent serologic evidence indicated virus circulation in dog breeds other than greyhounds, but the virus had not been isolated from affected animals. In 2005, we conducted virologic investigation of 7 nongreyhound dogs that died from respiratory disease in Florida and isolated influenza subtype H3N8 virus. Antigenic and genetic analysis of A/canine/Jacksonville/2005 (H3N8) and A/canine/Miami/2005 (H3N8) found similarity to earlier isolates from greyhounds, which indicates that canine influenza viruses are not restricted to greyhounds. The hemagglutinin contained 5 conserved amino acid differences that distinguish canine from equine lineages. The antigenic homogeneity of the canine viruses suggests that measurable antigenic drift has not yet occurred. Continued surveillance and antigenic analyses should monitor possible emergence of antigenic variants of canine influenza virus.

引用

页码：902 / 908

页数：7

共 17 条

[1]

[Anonymous], 1992, VIROLOGY LAB MANUAL

[2] Positive selection on the H3 hemagglutinin gene of human influenza virus A [J].