Detection of Clostridium difficile toxin:: Comparison of enzyme immunoassay results with results obtained by cytotoxicity assay

被引：57

作者：

Musher, Daniel M.

Manhas, Atisha

Jain, Pranav

Nuila, Franziska

Waqar, Amna

Logan, Nancy

Marino, Bernard

Graviss, Edward A.

机构：

[1] Vet Affairs Med Ctr, Infect Dis Sect, Med Serv, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Mol Virol, Houston, TX 77030 USA

[4] Baylor Coll Med, Dept Microbiol, Houston, TX 77030 USA

[5] Baylor Coll Med, Dept Pathol, Houston, TX 77030 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2007年 / 45卷 / 08期

关键词：

D O I：

10.1128/JCM.00686-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Several kinds of laboratory techniques are available to detect Clostridium difficile toxin in fecal samples. Because questions have been raised about the reliability of immunoassays compared to the accepted standard, cytotoxicity assay, we studied three enzyme immunoassays (EIAs) and one rapid EIA, which demonstrated relatively good sensitivities and specificities compared to cytotoxicity assay.

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页码：2737 / 2739

页数：3

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