42,43,44,45,46,47,55-Heptanor-41-oxohomoyessotoxin, a new biotoxin from mussels of the northern Adriatic sea

被引：34

作者：

Ciminiello, P

Fattorusso, E

Forino, M

Poletti, R

机构：

[1] Univ Naples Federico II, Dipartimento Chil Sostanze Nat, I-80131 Naples, Italy

[2] Ctr Ric Marine, I-47042 Cesenatico, FO, Italy

来源：

CHEMICAL RESEARCH IN TOXICOLOGY | 2001年 / 14卷 / 05期

关键词：

D O I：

10.1021/tx000259v

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The diarrhetic shellfish toxin composition in the digestive glands of mussels from the northern Adriatic sea was investigated. Along with known yessotoxins, identified by comparison of their chromatographic and spectral properties with those reported in the literature, we isolated a new analogue of yessotoxin, 42,43,44,45,46,47,55-heptanor-41-oxohomoyessotoxin, 1. Its structure was determined by H-1 NMR spectroscopy and mass spectrometry.

引用

页码：596 / 599

页数：4

共 14 条

[1] Anderson D.M., 1989, P11
[2] Structure determination of carboxyhomoyessotoxin, a new yessotoxin analogue isolated from adriatic mussels
Ciminiello, P
Fattorusso, E
Forino, M
Poletti, R
Viviani, R
[J]. CHEMICAL RESEARCH IN TOXICOLOGY, 2000, 13 (08) : 770 - 774
[3] Isolation of adriatoxin, a new analogue of yessotoxin from mussels of the Adriatic sea
Ciminiello, P
Fattorusso, E
Forino, M
Magno, S
Poletti, R
Viviani, R
[J]. TETRAHEDRON LETTERS, 1998, 39 (48) : 8897 - 8900
[4] Yessotoxin in mussels of the northern Adriatic Sea
Ciminiello, P
Fattorusso, E
Forino, M
Magno, S
Poletti, R
Satake, M
Viviani, R
Yasumoto, T
[J]. TOXICON, 1997, 35 (02) : 177 - 183
[5] Ciminiello P, 2000, EUR J ORG CHEM, V2000, P291
[6] OKADAIC ACID IN MUSSELS OF ADRIATIC SEA
FATTORUSSO, E
CIMINIELLO, P
COSTANTINO, V
MAGNO, S
MANGONI, A
MILANDRI, A
POLETTI, R
POMPEI, M
VIVIANI, R
[J]. MARINE POLLUTION BULLETIN, 1992, 24 (05) : 234 - 237
[7] A REVIEW OF HARMFUL ALGAL BLOOMS AND THEIR APPARENT GLOBAL INCREASE
HALLEGRAEFF, GM
[J]. PHYCOLOGIA, 1993, 32 (02) : 79 - 99
[8] BREVETOXIN B3, A NEW BREVETOXIN ANALOG ISOLATED FROM THE GREENSHELL MUSSEL PERNA-CANALICULUS INVOLVED IN NEUROTOXIC SHELLFISH POISONING IN NEW-ZEALAND
MOROHASHI, A
SATAKE, M
MURATA, K
NAOKI, H
KASPAR, HF
YASUMOTO, T
[J]. TETRAHEDRON LETTERS, 1995, 36 (49) : 8995 - 8998
[9] STRUCTURE AND PARTIAL STEREOCHEMICAL ASSIGNMENTS FOR MAITOTOXIN, THE MOST TOXIC AND LARGEST NATURAL NON-BIOPOLYMER
MURATA, M
NAOKI, H
MATSUNAGA, S
SATAKE, M
YASUMOTO, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (16) : 7098 - 7107
[10] NEGATIVE-ION FAST-ATOM-BOMBARDMENT TANDEM MASS-SPECTROMETRY FOR THE STRUCTURAL STUDY OF POLYETHER COMPOUNDS - STRUCTURAL VERIFICATION OF YESSOTOXIN
NAOKI, H
MURATA, M
YASUMOTO, T
[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1993, 7 (03) : 179 - 182

← 1 2 →