Incidence of seizures in patients with multiple sclerosis treated with intrathecal baclofen

被引：45

作者：

Schuele, SU

Kellinghaus, C

Shook, SJ

Boulis, N

Bethoux, FA

Loddenkemper, T

机构：

[1] Cleveland Clin Fdn, Dept Neurol S91, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA

来源：

NEUROLOGY | 2005年 / 64卷 / 06期

关键词：

D O I：

10.1212/01.WNL.0000154639.35941.21

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Oral and intrathecal baclofen (ITB) have been associated with epileptic seizures. The authors observed a higher incidence of epileptic seizures in 99 patients with multiple sclerosis ( MS) treated with ITB vs a matched control group (7% vs 1%, p < 0.05). Three patients with MS on ITB developed status epilepticus. Seizures were often associated with additional triggering factors.

引用

页码：1086 / 1087

页数：2

共 10 条

[1]

Bethoux FA, 2002, NEUROLOGY, V58, pA188

[2]

Dinnes J., 2003, HEALTH TECHNOL ASSES, V7, P1, DOI [DOI 10.3310/HTA7400, 10.3310/hta7400]

[3] Tiagabine-related non-convulsive status epilepticus in partial epilepsy:: three case reports and a review of the literature [J].