BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation

被引:64
作者
Cho, KWY [1 ]
Blitz, IL
机构
[1] Univ Calif Irvine, Dept Dev & Cell Biol, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Ctr Dev Biol, Irvine, CA 92697 USA
关键词
D O I
10.1016/S0959-437X(98)80116-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Bone morphogenetic proteins (BMPs), members of the TG F-P superfamily, have critical functions in many biological contexts. Recent findings in Drosophila and vertebrates suggest that BMP signaling can be modulated extracellularly and intracellularly by the availability of BMP inhibitors and Smads, respectively.
引用
收藏
页码:443 / 449
页数:7
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