Asymmetric phase-transfer alkylation catalyzed by a chiral quaternary phosphonium salt with a multiple hydrogen-bonding site

被引：95

作者：

Manabe, K ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 32期

关键词：

asymmetric reactions; hydrogen bonding; phase transfer; phosphonium salts;

D O I：

10.1016/S0040-4039(98)01181-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A chiral phosphonium salt has been synthesized as a novel phase-transfer catalyst, and used for asymmetric benzylation of t-butyl 2-oxocyclopentanecarboxylate to give the corresponding product with up to 50% ee. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5807 / 5810

页数：4

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