High intensity focused ultrasound (HIFU) for prostate cancer: Current clinical status, outcomes and future perspectives

被引：70

作者：

Crouzet, Sebastien ^{[1
]}

Murat, Francois J. ^{[2
]}

Pasticier, Gilles ^{[3
]}

Cassier, Philippe ^{[4
]}

Chapelon, Jean Y. ^{[5
,6
]}

Gelet, Albert ^{[7
]}

机构：

[1] Hop Edouard Herriot, Urol & Transplantat Dept, F-69437 Lyon 03, France

[2] Val dOuest Hosp, Dept Urol, Lyon, France

[3] Pellegrin Hosp, Dept Urol, Bordeaux, France

[4] Hop Edouard Herriot, Dept Med Oncol, F-69437 Lyon 03, France

[5] INSERM, Therapeut Ultrasound Res Lab, F-69008 Lyon, France

[6] Univ Lyon, Lyon, France

[7] Hop Edouard Herriot, Dept Urol, F-69437 Lyon 03, France

来源：

INTERNATIONAL JOURNAL OF HYPERTHERMIA | 2010年 / 26卷 / 08期

关键词：

high intensity focused ultrasound; localised prostate cancer; predition and monitoring of tumour response; thermal ablation; ultrasound surgery; TRANSRECTAL HIFU; DOSE-ESCALATION; RADIATION-THERAPY; BEAM RADIOTHERAPY; TREATMENT FAILURE; FOCAL THERAPY; TRIAL; MRI; EXPERIENCE; EXPERIMENTATION;

D O I：

10.3109/02656736.2010.498803

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Two devices are currently available for the treatment of prostate cancer with HIFU: Sonablate (R) and Ablatherm (R). The outcomes achieved for primary-care patient are very promissing with mid- and long-term progression-free survival rates around 70%, negative postoperative prostate biopsies almost 85%, and an excellent morbidity profile. Moreover, HIFU has a considerable potential for local recurrence after radiation failure. Recently, some early experiences on focal therapy suggest that HIFU could be an excellent option for highly selected patient.</.

引用

页码：796 / 803

页数：8

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