Natural history and clinical features of progressive supranuclear palsy: a clinical study

被引：14

作者：

Diroma, C ^{[1
]}

Dell'Aquila, C ^{[1
]}

Fraddosio, A ^{[1
]}

Lamberti, S ^{[1
]}

Mastronardi, R ^{[1
]}

Russo, I ^{[1
]}

De Mari, M ^{[1
]}

Iliceto, G ^{[1
]}

机构：

[1] Policlin, Neurol Clin 2, Bari, Italy

来源：

NEUROLOGICAL SCIENCES | 2003年 / 24卷 / 03期

关键词：

D O I：

10.1007/s10072-003-0117-z

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Progressive supranuclear palsy (PSP or Steele-Richardson-Olszewski syndrome) is one of the most-common types of atypical parkinsonism. To characterize the natural history and the clinical features of PSP, we reviewed the records of 25 patients followed in our clinic since 199 1, with a clinical diagnosis of PSP according to NINDS and Golbe criteria. Progressive onset of early bilateral bradykinesia and postural instability with falls during the 5th decade strongly support the diagnosis of PSP in our patients. Pseudobulbar symptoms are very common at onset and during the course of the illness.

引用

页码：176 / 177

页数：2

共 4 条

[1] Direct genetic evidence for involvement of tau in progressive supranuclear palsy [J].