Cell migration in 3D matrix

被引:370
作者
Even-Ram, S [1 ]
Yamada, KM [1 ]
机构
[1] Natl Inst Dent & Craniofacial Res, Craniofacial Dev Biol & Regenerat Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/j.ceb.2005.08.015
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The ability of cells to migrate within the extracellular matrix and to remodel it depends as much on the physical and biochemical characteristics of a particular matrix as on cellular properties. Analyzing the different modes of migration of cells in matrices, and how cells switch between these modes, is vital for understanding a variety of physiological and pathological processes. Recent work provides new insights, but also raises some debates about the mechanisms and regulation of cell migration in three-dimensional matrices.
引用
收藏
页码:524 / 532
页数:9
相关论文
共 49 条
[1]  
AMATANGELO DM, 2005, IN PRESS AM J PATHOL
[2]   Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors [J].
Beningo, KA ;
Dembo, M ;
Wang, YI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (52) :18024-18029
[3]   MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix [J].
Chun, TH ;
Sabeh, F ;
Ota, I ;
Murphy, H ;
McDonagh, KT ;
Holmbeck, K ;
Birkedal-Hansen, H ;
Allen, ED ;
Weiss, SJ .
JOURNAL OF CELL BIOLOGY, 2004, 167 (04) :757-767
[4]   Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan [J].
Clark, RAF ;
Lin, FB ;
Greiling, D ;
An, JQ ;
Couchman, JR .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 122 (02) :266-277
[5]   Cell interactions with three-dimensional matrices [J].
Cukierman, E ;
Pankov, R ;
Yamada, KM .
CURRENT OPINION IN CELL BIOLOGY, 2002, 14 (05) :633-639
[6]   Taking cell-matrix adhesions to the third dimension [J].
Cukierman, E ;
Pankov, R ;
Stevens, DR ;
Yamada, KM .
SCIENCE, 2001, 294 (5547) :1708-1712
[7]   Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice [J].
Drew, AF ;
Blick, TJ ;
Lafleur, MA ;
Tim, ELM ;
Robbie, MJ ;
Rice, GE ;
Quinn, MA ;
Thompson, EW .
GYNECOLOGIC ONCOLOGY, 2004, 95 (03) :437-448
[8]   Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions [J].
Fais, S ;
Malorni, W .
JOURNAL OF LEUKOCYTE BIOLOGY, 2003, 73 (05) :556-563
[9]  
Friedl P, 1998, MICROSC RES TECHNIQ, V43, P369, DOI 10.1002/(SICI)1097-0029(19981201)43:5<369::AID-JEMT3>3.0.CO
[10]  
2-6