GPSy: a cross-species gene prioritization system for conserved biological processes-application in male gamete development

被引：16

作者：

Britto, Ramona ^{[1
]}

Sallou, Olivier ^{[2
]}

Collin, Olivier ^{[2
]}

Michaux, Gregoire ^{[3
]}

Primig, Michael ^{[1
]}

Chalmel, Frederic ^{[1
]}

机构：

[1] Univ Rennes 1, INSERM, Irset, U1085, F-35043 Rennes, France

[2] Univ Rennes 1, Inst Rech Informat & Syst Aleatoires IRISA INRIA, F-35043 Rennes, France

[3] Univ Rennes 1, CNRS, UMR6061, F-35043 Rennes, France

来源：

NUCLEIC ACIDS RESEARCH | 2012年 / 40卷 / W1期

关键词：

POSITIONAL CANDIDATE GENES; COMPLEX HUMAN TRAITS; DISEASE-GENES; CAENORHABDITIS-ELEGANS; CHROMOSOME SYNAPSIS; EXPRESSION DATA; SPO11; GENE; NETWORK; DISCOVERY; SEQUENCE;

D O I：

10.1093/nar/gks380

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

We present gene prioritization system (GPSy), a cross-species gene prioritization system that facilitates the arduous but critical task of prioritizing genes for follow-up functional analyses. GPSy's modular design with regard to species, data sets and scoring strategies enables users to formulate queries in a highly flexible manner. Currently, the system encompasses 20 topics related to conserved biological processes including male gamete development discussed in this article. The web server-based tool is freely available at n http://gpsy.genouest.org.

引用

页码：W458 / W465

页数：8

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