The Gene Ontology in 2010: extensions and refinements The Gene Ontology Consortium

被引：328

作者：

Berardini, Tanya Z. ^{[1
]}

Li, Donghui ^{[1
]}

Huala, Eva ^{[1
]}

Bridges, Susan ^{[2
]}

Burgess, Shane ^{[2
]}

McCarthy, Fiona ^{[2
]}

Carbon, Seth ^{[3
]}

Lewis, Suzanna E. ^{[3
]}

Mungall, Christopher J. ^{[3
]}

Abdulla, Amina ^{[3
]}

Wood, Valerie ^{[4
]}

Feltrin, Erika ^{[5
]}

Valle, Giorgio ^{[5
]}

Chisholm, Rex L. ^{[6
]}

Fey, Petra ^{[6
]}

Gaudet, Pascale ^{[6
]}

Kibbe, Warren ^{[6
]}

Basu, Siddhartha ^{[6
]}

Bushmanova, Yulia ^{[6
]}

Eilbeck, Karen ^{[7
]}

Siegele, Deborah A. ^{[8
,9
]}

McIntosh, Brenley ^{[8
,9
]}

Renfro, Daniel ^{[8
,9
]}

Zweifel, Adrienne ^{[8
,9
]}

Hu, James C. ^{[8
,9
]}

Ashburner, Michael

Tweedie, Susan ^{[10
]}

Alam-Faruque, Yasmin ^{[11
,12
]}

Apweiler, Rolf ^{[11
,12
]}

Auchinchloss, Andrea ^{[11
,12
]}

Bairoch, Amos ^{[11
,12
]}

Barrell, Daniel ^{[11
,12
]}

Binns, David ^{[11
,12
]}

Blatter, Marie-Claude ^{[11
,12
]}

Bougueleret, Lydie ^{[11
,12
]}

Boutet, Emmanuel ^{[11
,12
]}

Breuza, Lionel ^{[11
,12
]}

Bridge, Alan ^{[11
,12
]}

Browne, Paul ^{[11
,12
]}

Chan, Wei Mun ^{[11
,12
]}

Coudert, Elizabeth ^{[11
,12
]}

Daugherty, Louise ^{[11
,12
]}

Dimmer, Emily ^{[11
,12
]}

Eberhardt, Ruth ^{[11
,12
]}

Estreicher, Anne ^{[11
,12
]}

Famiglietti, Livia ^{[11
,12
]}

Ferro-Rojas, Serenella ^{[11
,12
]}

Feuermann, Marc ^{[11
,12
]}

Foulger, Rebecca ^{[11
,12
]}

Gruaz-Gumowski, Nadine ^{[11
,12
]}

机构：

[1] Carnegie Inst Sci, TAIR, Dept Plant Biol, Stanford, CA USA

[2] Mississippi State Univ, AgBase, Mississippi State, MS USA

[3] LBNL, BBOP, Berkeley, CA USA

[4] Canc Res UK, London, England

[5] Univ Padua, CRIBI, I-35100 Padua, Italy

[6] Northwestern Univ, DictyBase, Chicago, IL 60611 USA

[7] Univ Utah, Eccles Inst Human Genet, Salt Lake City, UT USA

[8] Texas A&M Univ, Dept Biol, College Stn, TX 77843 USA

[9] Texas A&M Univ, Dept Biochem & Biophys, College Stn, TX 77843 USA

[10] Univ Cambridge, Dept Genet, FlyBase, Cambridge CB2 3EH, England

[11] GOA UniProtKB EBI, Hinxton, England

[12] SIB, Geneva, Switzerland

[13] GO EBI, Hinxton, England

[14] Oregon State Univ, Dept Bot & Plant Pathol, Corvallis, OR 97331 USA

[15] Univ Maryland, Sch Med, Inst Genome Sci, Baltimore, MD 21201 USA

[16] J Craig Venter Inst, Rockville, MD USA

[17] Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA

[18] Jackson Lab, MGI, Bar Harbor, ME 04609 USA

[19] Wells Coll, PAMGO, Aurora, NY USA

[20] Med Coll Wisconsin, RGD, Milwaukee, WI 53226 USA

[21] NYU, Dept Biochem, Sch Med, New York, NY 10016 USA

[22] Stanford Univ, Dept Genet, SGD, Stanford, CA 94305 USA

[23] Wellcome Trust Sanger Inst, Hinxton, England

[24] CALTECH, WormBase, Pasadena, CA 91125 USA

[25] UCL, London, England

[26] Univ Oregon, ZFIN, Eugene, OR 97403 USA

来源：

NUCLEIC ACIDS RESEARCH | 2010年 / 38卷

基金：

英国医学研究理事会; 美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1093/nar/gkp1018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the GO domains. These improve the representation of biology, facilitate querying, and allow GO developers to systematically check for and correct inconsistencies within the GO. Gene product annotation using GO continues to increase both in the number of total annotations and in species coverage. GO tools, such as OBO-Edit, an ontology-editing tool, and AmiGO, the GOC ontology browser, have seen major improvements in functionality, speed and ease of use.

引用

页码：D331 / D335

页数：5

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