Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patients under various clinical conditions

被引：48

作者：

Aberle, SW

Kletzmayr, J

Watschinger, B

Schmied, B

Vetter, N

Puchhammer-Stöckl, E

机构：

[1] Univ Vienna, Inst Virol, A-1095 Vienna, Austria

[2] Univ Vienna, Dept Med, Div Nephrol & Dialysis, A-1095 Vienna, Austria

[3] Pulmol Zentrum, Vienna, Austria

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2001年 / 39卷 / 05期

关键词：

D O I：

10.1128/JCM.39.5.1972-1974.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A line probe assay (INNO-LiPA HBV BR) detecting drug-resistant hepatitis B virus (HBV) strains was evaluated, Results concordant with sequence analysis were obtained with 48 of 56 serum samples from HBV-infected patients undergoing lamivudine therapy. In eight cases, additional minor subpopulations could be identified by the line probe assay.

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页码：1972 / 1974

页数：3

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