Clean three-step synthesis of 4,5-dihydro-1H-pyrazoles starting from alcohols using polymer supported reagents

被引：45

作者：

Haunert, F ^{[1
]}

Bolli, MH ^{[1
]}

Hinzen, B ^{[1
]}

Ley, SV ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 15期

关键词：

D O I：

10.1039/a803609h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nafion-TMS mediated Mukaiyama aldol reaction of silyl enol ethers with aldehydes, obtained from mild oxidation of alcohols with polymer supported perruthenate (PSP), yielded alpha,beta-unsaturated ketones, which upon treatment with hydrazines allowed the clean synthesis of 4,5-dihydro-1H-pyrazoles.

引用

页码：2235 / 2237

页数：3

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