Human-animal chimeras in biomedical research

被引：43

作者：

Behringer, Richard R. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Mol Genet, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Ctr Stem Cell & Dev Biol, Houston, TX 77030 USA

来源：

CELL STEM CELL | 2007年 / 1卷 / 03期

关键词：

D O I：

10.1016/j.stem.2007.07.021

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have tissues derived from different species. The biological consequences of human-animal chimeras have become an issue of ethical debate. Ironically, human-animal chimeras with human blood, neurons, germ cells, and other tissues have been generated for decades. This has facilitated human biological studies and therapeutic strategies for disease.

引用

页码：259 / 262

页数：4

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