Feasibility of quality of life assessment in patients with upper gastrointestinal tract cancer

被引:22
作者
Blazeby, JM [1 ]
Nicklin, J
Brookes, ST
Winstone, K
Alderson, D
机构
[1] Univ Bristol, Bristol Royal Infirm, Div Surg, Bristol BS2 8HW, Avon, England
[2] Univ Bristol, Dept Social Med, Bristol BS8 2PR, Avon, England
基金
英国医学研究理事会;
关键词
quality of life; EORTC QLQ-C30; compliance; upper gastrointestinal cancer;
D O I
10.1038/sj.bjc.6601146
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Quality of life (QOL) is an important outcome after treatment for upper gastrointestinal tract cancer but few studies report good accrual and subsequent attrition is usually high. This study investigated the feasibility of a nurse-led service to obtain longitudinal QOL assessments and explored how clinical and sociodemographic factors influence patients' need for help to complete questionnaires. Fully informed patients were invited into the study. Baseline hospital assessments were scheduled by telephone and thereafter by post unless patients' health indicated the need for a home visit. In all, 128 out of 140 (91%) baseline QOL assessments were performed. Follow-up questionnaire completion was good, with 114 patients (89%) completing all but one of the expected assessments. At baseline, 41 (32%) patients required a lot of help to complete questionnaires. Patients requiring help were more likely to be undergoing palliative treatment than treatment aimed at cure (68 vs 33%; odds ratio 3.48, P<0.01). Patients' with advanced stage cancer of the upper gastrointestinal tract receiving palliative treatment require dedicated staff to ensure good compliance with longitudinal QOL data collection. It is essential to budget for this in clinical trails.
引用
收藏
页码:497 / 501
页数:5
相关论文
共 22 条
[1]   THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY [J].
AARONSON, NK ;
AHMEDZAI, S ;
BERGMAN, B ;
BULLINGER, M ;
CULL, A ;
DUEZ, NJ ;
FILIBERTI, A ;
FLECHTNER, H ;
FLEISHMAN, SB ;
DEHAES, JCJM ;
KAASA, S ;
KLEE, M ;
OSOBA, D ;
RAZAVI, D ;
ROFE, PB ;
SCHRAUB, S ;
SNEEUW, K ;
SULLIVAN, M ;
TAKEDA, F .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (05) :365-376
[2]  
[Anonymous], 1996, J Clin Oncol, V14, P671
[3]  
BARR H, 1991, CANCER, V68, P1660, DOI 10.1002/1097-0142(19911001)68:7<1660::AID-CNCR2820680733>3.0.CO
[4]  
2-L
[5]   Clinical relevance of single item quality of life indicators in cancer clinical trials [J].
Bernhard, J ;
Sullivan, M ;
Hürny, C ;
Coates, AS ;
Rudenstam, CM .
BRITISH JOURNAL OF CANCER, 2001, 84 (09) :1156-1165
[6]   Clinical and psychometric validation of an EORTC questionnaire module, the EORTC QLQ-OES18, to assess quality of life in patients with oesophageal cancer [J].
Blazeby, JM ;
Conroy, T ;
Hammerlid, E ;
Fayers, P ;
Sezer, O ;
Koller, M ;
Arraras, J ;
Bottomley, A ;
Vickery, CW ;
Etienne, PL ;
Alderson, D .
EUROPEAN JOURNAL OF CANCER, 2003, 39 (10) :1384-1394
[7]   Development of an EORTC questionnaire module to be used in quality of life assessment for patients with oesophageal cancer [J].
Blazeby, JM ;
Alderson, D ;
Winstone, K ;
Steyn, R ;
Hammerlid, E ;
Arraras, J ;
Farndon, JR .
EUROPEAN JOURNAL OF CANCER, 1996, 32A (11) :1912-1917
[8]   Quality of life evaluation in oncological clinical trials - the EORTC model [J].
de Haes, J ;
Curran, D ;
Young, T ;
Bottomley, A ;
Flechtner, H ;
Aaronson, N ;
Blazeby, J ;
Bjordal, K ;
Brandberg, Y ;
Greimel, E ;
Maher, J ;
Sprangers, M ;
Cull, A .
EUROPEAN JOURNAL OF CANCER, 2000, 36 (07) :821-825
[9]   Quality of life assessment in daily clinical oncology practice: A feasibility study [J].
Detmar, SB ;
Aaronson, NK .
EUROPEAN JOURNAL OF CANCER, 1998, 34 (08) :1181-1186
[10]   How are you feeling? Who wants to know? Patients' and oncologists' preferences for discussing health-related quality-of-life issues [J].
Detmar, SB ;
Aaronson, NK ;
Wever, LDV ;
Muller, M ;
Schornagel, JH .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (18) :3295-3301