DELLAs Modulate Jasmonate Signaling via Competitive Binding to JAZs

被引:645
作者
Hou, Xingliang [1 ,2 ]
Lee, Li Yen Candy [1 ,2 ]
Xia, Kuaifei [1 ,2 ,3 ]
Yen, Yuanyuan [1 ,2 ]
Yu, Hao [1 ,2 ]
机构
[1] Natl Univ Singapore, Dept Biol Sci, Singapore 117543, Singapore
[2] Natl Univ Singapore, Temasek Life Sci Lab, Singapore 117543, Singapore
[3] Chinese Acad Sci, S China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
关键词
ARABIDOPSIS MESOPHYLL PROTOPLASTS; PHYTOCHROME INTERACTING FACTOR-3; FLOWERING TIME GENES; REGULATED DEFENSE; PLANT-RESPONSES; GROWTH; LIGHT; PROTEINS; COI1; TRANSDUCTION;
D O I
10.1016/j.devcel.2010.10.024
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Gibberellins (GAs) modulate jasmonate (JA) signaling, which is essential for stress response and development in plants. However, the molecular details of such phytohormone interaction remain largely unknown. Here, we show that the JA ZIM-domain 1 (JAZ1) protein, a key repressor of JA signaling, interacts in vivo with DELLA proteins, repressors of the GA pathway. DELLAs prevent inhibitory JAZ1 interaction with a key transcriptional activator of JA responses, MYC2, and, thus, enhance the ability of MYC2 to regulate its target genes. Conversely, GA triggers degradation of DELLAs, which allows JAZ1 to bind MYC2 and suppress MYC2-dependent JA-signaling outputs. Therefore, our results reveal one means by which GAs suppress cellular competence to respond to JA. Because DELLAs serve as central regulators that mediate the crosstalk of various phytohormones, our model also suggests a candidate mechanism by which JA signaling may be fine-tuned by other signaling pathways through DELLAs.
引用
收藏
页码:884 / 894
页数:11
相关论文
共 54 条
[1]   Integration of plant responses to environmentally activated phytohormonal signals [J].
Achard, P ;
Cheng, H ;
De Grauwe, L ;
Decat, J ;
Schoutteten, H ;
Moritz, T ;
Van Der Straeten, D ;
Peng, JR ;
Harberd, NP .
SCIENCE, 2006, 311 (5757) :91-94
[2]   Ethylene regulates Arabidopsis development via the modulation of DELLA protein growth repressor function [J].
Achard, P ;
Vriezen, WH ;
Van Der Straeten, D ;
Harberd, NP .
PLANT CELL, 2003, 15 (12) :2816-2825
[3]   Plant DELLAs restrain growth and promote survival of adversity by reducing the levels of reactive oxygen species [J].
Achard, Patrick ;
Renou, Jean-Pierre ;
Berthome, Richard ;
Harberd, Nicholas P. ;
Genschik, Pascal .
CURRENT BIOLOGY, 2008, 18 (09) :656-660
[4]   Constitutive photomorphogenesis 1 and multiple photoreceptors control degradation of phytochrome interacting factor 3, a transcription factor required for light signaling in Arabidopsis [J].
Bauer, D ;
Viczián, A ;
Kircher, S ;
Nobis, T ;
Nitschke, R ;
Kunkel, T ;
Panigrahi, KCS ;
Adám, É ;
Fejes, E ;
Schäfer, E ;
Nagy, F .
PLANT CELL, 2004, 16 (06) :1433-1445
[5]   The role of GRAS proteins in plant signal transduction and development [J].
Bolle, C .
PLANTA, 2004, 218 (05) :683-692
[6]   Conserved MYC transcription factors play a key role in jasmonate signaling both in tomato and Arabidopsis [J].
Boter, M ;
Ruíz-Rivero, O ;
Abdeen, A ;
Prat, S .
GENES & DEVELOPMENT, 2004, 18 (13) :1577-1591
[7]   A role for the GCC-box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis [J].
Brown, RL ;
Kazan, K ;
McGrath, KC ;
Maclean, DJ ;
Manners, JM .
PLANT PHYSIOLOGY, 2003, 132 (02) :1020-1032
[8]   New weapons and a rapid response against insect attack [J].
Browse, John ;
Howe, Gregg A. .
PLANT PHYSIOLOGY, 2008, 146 (03) :832-838
[9]   Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in arabidopsis [J].
Cao, Dongni ;
Cheng, Hui ;
Wu, Wei ;
Soo, Hui Meng ;
Peng, Jinrong .
PLANT PHYSIOLOGY, 2006, 142 (02) :509-525
[10]   Gibberellin Acts through Jasmonate to Control the Expression of MYB21, MYB24, and MYB57 to Promote Stamen Filament Growth in Arabidopsis [J].
Cheng, Hui ;
Song, Susheng ;
Xiao, Langtao ;
Soo, Hui Meng ;
Cheng, Zhiwei ;
Xie, Daoxin ;
Peng, Jinrong .
PLOS GENETICS, 2009, 5 (03)