Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility

被引：135

作者：

Weedon, MN

Schwarz, PEH

Horikawa, Y

Iwasaki, N

Illig, T

Holle, R

Rathmann, W

Selisko, T

Schulze, J

Owen, KR

Evans, J

Bosque-Plata, LD

Hitman, G

Walker, M

Levy, JC

Sampson, M

Bell, GI

McCarthy, MI

Hattersley, AT

Frayling, TM

机构：

[1] Peninsula Med Sch, Dept Diabet Res & Vasc Med, Exeter, Devon, England

[2] Tech Univ Dresden, Med Fac Carl Gustav Carus, Dept Endocrinopathies & Metab Dis, D-8027 Dresden, Germany

[3] Gunma Univ, Inst Mol & Cellular Regulat, Dept Cell Biol, Gunma, Japan

[4] Tokyo Womens Med Univ, Ctr Diabet, Tokyo, Japan

[5] GSF, Natl Res Ctr Environm & Hlth, Inst Epidemiol, Neuherberg, Germany

[6] GSF, Natl Res Ctr Environm & Hlth, Inst Hlth Econ & Hlth Care Management, Neuherberg, Germany

[7] German Diabet Res Inst, Dept Biometry & Epidemiol, Dusseldorf, Germany

[8] Univ Chicago, Dept Biochem & Mol Biol, Chicago, IL 60637 USA

[9] Univ London, Queen Mary Sch Med & Dent, Barts & London, Dept Diabet & Metab Med, London, England

[10] Med Sch Newcastle Upon Tyne, Dept Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[11] Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England

[12] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England

[13] Univ Oxford, Radcliffe Infirm, Diabet Res Labs, Oxford OX2 6HE, England

[14] Ctr Diabet, Norwich, Norfolk, England

来源：

AMERICAN JOURNAL OF HUMAN GENETICS | 2003年 / 73卷 / 05期

关键词：

D O I：

10.1086/379285

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：1208 / 1212

页数：5

共 24 条

[1] The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes [J].

Altshuler, D ;

Hirschhorn, JN ;

Klannemark, M ;

Lindgren, CM ;

Vohl, MC ;

Nemesh, J ;

Lane, CR ;

Schaffner, SF ;

Bolk, S ;

Brewer, C ;

Tuomi, T ;

Gaudet, D ;

Hudson, TJ ;

Daly, M ;

Groop, L ;

Lander, ES .

NATURE GENETICS, 2000, 26 (01) :76-80

[2] A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance [J].

Baier, LJ ;

Permana, PA ;

Yang, XL ;

Pratley, RE ;

Hanson, RL ;

Shen, GQ ;

Mott, D ;

Knowler, WC ;

Cox, NJ ;

Horikawa, Y ;

Oda, N ;

Bell, GI ;

Bogardus, C .

JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (07) :R69-R73

[3] Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians [J].

Cassell, PG ;

Jackson, AE ;

North, BV ;

Evans, JC ;

Syndercombe-Court, D ;

Phillips, C ;

Ramachandran, A ;

Snehalatha, C ;

Gelding, SV ;

Vijayaravaghan, S ;

Curtis, D ;

Hitman, GA .

DIABETES, 2002, 51 (05) :1622-1628

[4] Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese [J].

Daimon, M ;

Oizumi, T ;

Saitoh, T ;

Kameda, W ;

Yamaguchi, H ;

Ohnuma, H ;

Igarashi, M ;

Manaka, H ;

Kato, T .

DIABETES RESEARCH AND CLINICAL PRACTICE, 2002, 56 (02) :147-152

[5] Bias in meta-analysis detected by a simple, graphical test [J].

Egger, M ;

Smith, GD ;

Schneider, M ;

Minder, C .

BMJ-BRITISH MEDICAL JOURNAL, 1997, 315 (7109) :629-634

[6] Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians [J].

Elbein, SC ;

Chu, W ;

Ren, QF ;

Hemphill, C ;

Schay, J ;

Cox, NJ ;

Hanis, CL ;

Hasstedt, SJ .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (02) :650-654

[7] Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom [J].

Evans, JC ;

Frayling, TM ;

Cassell, PG ;

Saker, PJ ;

Hitman, GA ;

Walker, M ;

Levy, JC ;

O'Rahilly, S ;

Rao, PVS ;

Bennett, AJ ;

Jones, EC ;

Menzel, S ;

Prestwich, P ;

Simecek, N ;

Wishart, M ;

Dhillon, R ;

Fletcher, C ;

Millward, A ;

Demaine, A ;

Wilkin, T ;

Horikawa, Y ;

Cox, NJ ;

Bell, GI ;

Ellard, S ;

McCarthy, MI ;

Hattersley, AT .

AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (03) :544-552

[8] Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort [J].

Fingerlin, TE ;

Erdos, MR ;

Watanabe, RM ;

Wiles, KR ;

Stringham, HM ;

Mohlke, KL ;

Silander, K ;

Valle, TT ;

Buchanan, TA ;

Tuomilehto, J ;

Bergman, RN ;

Boehnke, M ;

Collins, FS .

DIABETES, 2002, 51 (05) :1644-1648

[9] SNP43 of CAPN10 and the risk of type 2 diabetes in African-Americans -: The atherosclerosis risk in communities study [J].

Garant, MJ ;

Kao, WHL ;

Brancati, F ;

Coresh, J ;

Rami, TM ;

Hanis, CL ;

Boerwinkle, E ;

Shuldiner, AR .

DIABETES, 2002, 51 (01) :231-237

[10] Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes [J].

Gloyn, AL ;

Weedon, MN ;

Owen, KR ;

Turner, MJ ;

Knight, BA ;

Hitman, G ;

Walker, M ;

Levy, JC ;

Sampson, M ;

Halford, S ;

McCarthy, MI ;

Hattersley, AT ;

Frayling, TM .

DIABETES, 2003, 52 (02) :568-572

← 1 2 3 →