Hot and cold spots of recombination in the human genome: The reason we should find them and how this can be achieved

被引:67
作者
Arnheim, N [1 ]
Calabrese, P [1 ]
Nordborg, M [1 ]
机构
[1] Univ So Calif, Mol & Computat Biol Program, Los Angeles, CA 90089 USA
关键词
D O I
10.1086/376419
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:5 / 16
页数:12
相关论文
共 101 条
  • [1] NONRANDOM ASSOCIATION OF POLYMORPHIC RESTRICTION SITES IN THE BETA-GLOBIN GENE-CLUSTER
    ANTONARAKIS, SE
    BOEHM, CD
    GIARDINA, PJV
    KAZAZIAN, HH
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (01): : 137 - 141
  • [2] Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion
    Ardlie, K
    Liu-Cordero, SN
    Eberle, MA
    Daly, M
    Barrett, J
    Winchester, E
    Lander, ES
    Kruglyak, L
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (03) : 582 - 589
  • [3] Patterns of linkage disequilibrium in the human genome
    Ardlie, KG
    Kruglyak, L
    Seielstad, M
    [J]. NATURE REVIEWS GENETICS, 2002, 3 (04) : 299 - 309
  • [4] Crossover breakpoint mapping identifies a subtelomeric hotspot for male meiotic recombination
    Badge, RM
    Yardley, J
    Jeffreys, AJ
    Armour, JAL
    [J]. HUMAN MOLECULAR GENETICS, 2000, 9 (08) : 1239 - 1244
  • [5] BOTSTEIN D, 1980, AM J HUM GENET, V32, P314
  • [6] Comprehensive human genetic maps: Individual and sex-specific variation in recombination
    Broman, KW
    Murray, JC
    Sheffield, VC
    White, RL
    Weber, JL
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 63 (03) : 861 - 869
  • [7] Genetic analysis of meiotic recombination in humans by use of sperm typing: Reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3
    Brown, GM
    Leversha, M
    Hulten, M
    Ferguson-Smith, MA
    Affara, NA
    Furlong, RA
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 62 (06) : 1484 - 1492
  • [8] Meiotic recombination and flanking marker exchange at the highly unstable human minisatellite CEB1 (D2S90)
    Buard, J
    Shone, AC
    Jeffreys, AJ
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (02) : 333 - 344
  • [9] INTEGRATED HUMAN GENOME-WIDE MAPS CONSTRUCTED USING THE CEPH REFERENCE PANEL
    BUETOW, KH
    WEBER, JL
    LUDWIGSEN, S
    SCHERPBIERHEDDEMA, T
    DUYK, GM
    SHEFFIELD, VC
    WANG, ZY
    MURRAY, JC
    [J]. NATURE GENETICS, 1994, 6 (04) : 391 - 393
  • [10] Using haplotype blocks to map human complex trait loci
    Cardon, LR
    Abecasis, GR
    [J]. TRENDS IN GENETICS, 2003, 19 (03) : 135 - 140