Involvement of the mevalonic acid pathway and the glyceraldehyde-pyruvate pathway in terpenoid biosynthesis of the liverworts Ricciocarpos natans and Conocephalum conicum

被引：48

作者：

Adam, KP ^{[1
]}

Thiel, R ^{[1
]}

Zapp, J ^{[1
]}

Becker, H ^{[1
]}

机构：

[1] Univ Saarland, D-66041 Saarbrucken, Germany

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1998年 / 354卷 / 01期

关键词：

isopentenyl diphosphate; mevalonic acid pathway; glyceraldehyde-pyruvate pathway; monoterpene; sesquiterpene; phytol; stigmasterol; C-13-labeling; liverwort; Ricciocarpos natans; Conocephalum conicum;

D O I：

10.1006/abbi.1998.0666

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The incorporation of C-13-labeled glucose into borneol, bornyl acetate, the sesquiterpenes cubebanol and ricciocarpin A, phytol, and stigmasterol has been studied in axenic cultures of the liverworts Ricciocarpos natans and Conocephalum conicum. Quantitative C-13 NMR spectroscopic analysis of the resulting labeling patterns showed that the isoprene building blocks of the sesquiterpenes and stigmasterol are built up via the mevalonic acid pathway, whereas the isoprene units of the monoterpenes and the diterpene phytol are exclusively derived from the glyceraldehyde-pyruvate pathway, These results indicate the involvement of both isopentenyl diphosphate biosynthetic pathways in different cellular compartments. (C) 1998 Academic Press.

引用

页码：181 / 187

页数：7