Covalent hemin-DNA adducts for generating a novel class of artificial heme enzymes

被引：112

作者：

Fruk, L ^{[1
]}

Niemeyer, CM ^{[1
]}

机构：

[1] Univ Dortmund, Fachbereich Chem, D-44227 Dortmund, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 17期

关键词：

DNA; enzymes; heme proteins; immobilization; self-assembly;

D O I：

10.1002/anie.200462567

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Well-defined conjugates between DNA and heme enzymes are accessible by the reconstitution of apo-enzymes with covalent hemin-DNA adducts (see picture). This concept allows access to novel redox catalysts with programmable binding properties that may be applied as biocatalysts, sensors, and biomaterials. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2603 / 2606

页数：4

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