High and low frequency electrical stimulation in non-lesional temporal lobe epilepsy

被引：70

作者：

Boex, Colette ^{[1
]}

Vulliemoz, Serge

Spinelli, Laurent

Polio, Claudio

Seeck, Margitta

机构：

[1] Univ Hosp Geneva, Dept Neurol, CH-1211 Geneva 14, Switzerland

[2] Univ Hosp Geneva, Dept Neurol, Presurg Epilepsy Evaluat Unit, Geneva, Switzerland

[3] Univ Lausanne Hosp, Dept Neurosurg, Lausanne, Switzerland

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2007年 / 16卷 / 08期

关键词：

deep brain stimulation; epilepsy;

D O I：

10.1016/j.seizure.2007.05.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In patients with pharmacologically intractable epilepsy who are not eligible for surgery, deep brain stimulation is currently under evaluation as an alternative treatment. Optimal stimulation parameters, including high (HFS) versus low frequency (LFS) stimulation, are notwell defined. Here, we report the effects of HFS (130 pulses per second, pps) and LFS (5 pps) of the principal epileptogenic focus, in three patients with non-lesional temporal lobe epilepsy. HFS, but not LFS, was associated with a reduction of the interictal discharges and absence of seizures. HFS may be beneficial in patients with non-lesional temporal lobe epilepsy who are not surgical candidates. (c) 2007 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

页码：664 / 669

页数：6

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