BF2-Chelated Tetraarylazadipyrromethenes as NIR Fluorochromes

被引:67
作者
Tasior, Mariusz [1 ]
O'Shea, Donal F. [1 ]
机构
[1] Univ Coll Dublin, Sch Chem & Chem Biol, Ctr Synth & Chem Biol, Dublin 4, Ireland
基金
爱尔兰科学基金会;
关键词
PHOTODYNAMIC THERAPY; SUCCINIMIDYL ESTERS; LABELING REAGENTS; BEHAVIOR; AGENTS; DYES;
D O I
10.1021/bc100051p
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis and properties of a new visible red/near-infrared fluorochrome for bioconjugation via activated ester groups is described. Representative amine conjugations with amino acid lysine and proteins lysozyme and trypsin were successfully accomplished.
引用
收藏
页码:1130 / 1133
页数:4
相关论文
共 23 条
[21]   Changes in retention behavior of fluorescently labeled proteins during ion-exchange chromatography caused by different protein surface labeling positions [J].
Teske, Christopher A. ;
Simon, Robert ;
Niebisch, Axel ;
Hubbuch, Juergen .
BIOTECHNOLOGY AND BIOENGINEERING, 2007, 98 (01) :193-200
[22]   Tumor paint:: A Chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci [J].
Veiseh, Mandana ;
Gabikian, Patrik ;
Bahrami, S-Bahram ;
Veiseh, Omid ;
Zhang, Miqin ;
Hackman, Robert C. ;
Ravanpay, Ali C. ;
Stroud, Mark R. ;
Kusuma, Yumiko ;
Hansen, Stacey J. ;
Kwok, Deborah ;
Munoz, Nina M. ;
Sze, Raymond W. ;
Grady, William M. ;
Greenberg, Norman M. ;
Ellenbogen, Richard G. ;
Olson, James M. .
CANCER RESEARCH, 2007, 67 (14) :6882-6888
[23]   Seminaphthofluorones are a family of water-soluble, low molecular weight, NIR-emitting fluorophores [J].
Yang, Youjun ;
Lowry, Mark ;
Xu, Xiangyang ;
Escobedo, Jorge O. ;
Sibrian-Vazcluez, Martha ;
Wong, Lisa ;
Schowalter, Corin M. ;
Jensen, Timothy J. ;
Fronczek, Frank R. ;
Warner, Isiah M. ;
Strongin, Robert M. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (26) :8829-8834