Improved procedure for the purification of PEG bound molecules by the use of trioctylamine

被引：33

作者：

Benaglia, M

Cinquini, M

Cozzi, F

机构：

[1] Univ Milan, Ctr CNR, I-20133 Milan, Italy

[2] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 10期

关键词：

soluble polymer-supported synthesis;

D O I：

10.1016/S0040-4039(99)00106-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of trioctylamine instead of triethylamine in reactions in which their hydrochlorides are formed simplifies purification and analytical procedures in the synthesis of small organic molecules on PEG supports. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2019 / 2020

页数：2

共 5 条

[1] STEREOSELECTIVE SYNTHESIS OF BETA-LACTAMS BY CONDENSATION OF TITANIUM ENOLATES OF 2-PYRIDYL THIOESTERS WITH IMINES
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[5] Expanding on the purification methodology of polyethylene glycol (PEG) bound molecules: The synthesis of 3,5-pyrazolidinediones
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[J]. TETRAHEDRON LETTERS, 1998, 39 (46) : 8433 - 8436

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