Ti(III)-catalyzed radical cyclization of 6,7-epoxygeranyl acetate

被引：31

作者：

Fuse, S ^{[1
]}

Hanochi, M ^{[1
]}

Doi, T ^{[1
]}

Takahashi, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 09期

关键词：

D O I：

10.1016/j.tetlet.2003.12.138

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reductive cyclization of epoxygeranyl acetate (1) was investigated using a catalytic amount of Cp2TiCl with various additives. The newly developed Cp2TiCl-Mn-lutidine.HCl-BEt3 system was found to be as effective as the reported stoichiometric system to afford the cyclized dehydro products 4 and 5 with 72% selectivity. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1961 / 1963

页数：3

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