The dynamics of histone H1 function in chromatin

被引：190

作者：

Bustin, M ^{[1
]}

Catez, F ^{[1
]}

Lim, JH ^{[1
]}

机构：

[1] NCI, NIH, Prot Sect, Lab Metab, Bethesda, MD 20892 USA

来源：

MOLECULAR CELL | 2005年 / 17卷 / 05期

关键词：

D O I：

10.1016/j.molcel.2005.02.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Over 80% of the nucleosomes in chromatin contain histone H1, a protein family known to affect the structure and activity of chromatin. Genetic studies and in vivo imaging experiments are changing the traditional view of H1 function and mechanism of action. H1 variants are partially redundant, mobile molecules that interact with nucleosomes as members of a dynamic protein network and serve as fine tuners of chromatin function.

引用

页码：617 / 620

页数：4

共 21 条

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