Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency

被引:60
作者
Matern, D
Hart, P
Murtha, AP
Vockley, J
Gregersen, N
Millington, DS
Treem, WR
机构
[1] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Med Genet, Rochester, MN 55905 USA
[3] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA
[4] Duke Univ, Med Ctr, Dept Obstet, Durham, NC 27710 USA
[5] Univ Aarhus, Res Unit Mol Genet, Aarhus, Denmark
关键词
D O I
10.1067/mpd.2001.111814
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
There is a correlation between pregnancy complications such as acute fatty liver of pregnancy and long-chain 3-hydroxyacl-coenzyme A dehydrogenase (LCHAD) deficiency. We diagnosed another fatty acid beta -oxidation defect, short-chain acyl-coenzyme A dehydrogenase deficiency, in an infant when evaluating him because his mother had acute fatty liver of pregnancy. Other beta -oxidation defects, in addition to LCHAD deficiency, should be considered in children born after pregnancies complicated by liver disease.
引用
收藏
页码:585 / 588
页数:4
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