Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency

There is a correlation between pregnancy complications such as acute fatty liver of pregnancy and long-chain 3-hydroxyacl-coenzyme A dehydrogenase (LCHAD) deficiency. We diagnosed another fatty acid beta -oxidation defect, short-chain acyl-coenzyme A dehydrogenase deficiency, in an infant when evaluating him because his mother had acute fatty liver of pregnancy. Other beta -oxidation defects, in addition to LCHAD deficiency, should be considered in children born after pregnancies complicated by liver disease.