Endogenous cannabinoids: Structure and metabolism

被引：94

作者：

Bisogno, T. ^{[1
]}

机构：

[1] CNR, Ist Chim Biomol, Endocannabinoid Res Grp, Naples, Italy

来源：

JOURNAL OF NEUROENDOCRINOLOGY | 2008年 / 20卷

关键词：

endocannabinoids; anandamide; 2-arachidonoylglycerol;

D O I：

10.1111/j.1365-2826.2008.01676.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The finding of specific binding sites for Delta(9)-tetrahydrocannabinol, the psychoactive component of Cannabis sativa, has led to the discovery of the endocannabinoid system and has emphasised the physiological and pathological relevance of endocannabidoid lipid signalling. Subsequently, an increasing number of papers have been published on the biochemistry and pharmacology of endocannabinoids. An overview of the current understanding of structure and metabolism of the best studied endocannabinoids is provided, with a focus on the mechanisms responsible for their biosynthesis and inactivation.

引用

页码：1 / 9

页数：9

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