The function and synthesis of ribosomes

被引：162

作者：

Lafontaine, DLJ

Tollervey, D

机构：

[1] Free Univ Brussels, Dept Biol Mol, FNRS, IRMW, B-1070 Brussels, Belgium

[2] Univ Edinburgh, Wellcome Trust, Ctr Cell Biol, Edinburgh EH9 3JR, Midlothian, Scotland

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 07期

关键词：

D O I：

10.1038/35080045

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Structural analyses of the large and small ribosomal subunits have allowed us to think about how they work in more detail than ever before. The mechanisms that underlie ribosomal synthesis, translocation and catalysis are now being unravelled, with practical implications for the design of antibiotics.

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收藏

页码：514 / 520

页数：7

相关论文

共 64 条

[31] Quality control mechanisms during translation [J].

Ibba, M ;

Söll, D .

SCIENCE, 1999, 286 (5446) :1893-1897

[32] Characterization of functionally active subribosomal particles from Thermus aquaticus [J].

Khaitovich, P ;

Mankin, AS ;

Green, R ;

Lancaster, L ;

Noller, HF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (01) :85-90

[33]

Kressler D, 1999, MOL CELL BIOL, V19, P7897

[34] Birth of the snoRNPs: the evolution of the modification-guide snoRNAs [J].

Lafontaine, DLJ ;

Tollervey, D .

TRENDS IN BIOCHEMICAL SCIENCES, 1998, 23 (10) :383-388

[35] Maturation of 23S ribosomal RNA requires the exoribonuclease RNase T [J].

Li, ZW ;

Pandit, S ;

Deutscher, MP .

RNA, 1999, 5 (01) :139-146

[36] RNase G (CafA protein) and RNase E are both required for the 5′ maturation of 16S ribosomal RNA [J].

Li, ZW ;

Pandit, S ;

Deutscher, MP .

EMBO JOURNAL, 1999, 18 (10) :2878-2885

[37] The Escherichia coli large ribosomal subunit at 7.5 Å resolution [J].

Matadeen, R ;

Patwardhan, A ;

Gowen, B ;

Orlova, EV ;

Pape, T ;

Cuff, M ;

Mueller, F ;

Brimacombe, R ;

van Heel, M .

STRUCTURE, 1999, 7 (12) :1575-1583

[38] Nuclear export of the small ribosomal subunit requires the Ran-GTPase cycle and certain nucleoporins [J].

Moy, TI ;

Silver, PA .

GENES & DEVELOPMENT, 1999, 13 (16) :2118-2133

[39] The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 Å resolution [J].

Mueller, F ;

Sommer, I ;

Baranov, P ;

Matadeen, R ;

Stoldt, M ;

Wöhnert, J ;

Görlach, M ;

van Heel, M ;

Brimacombe, R .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 298 (01) :35-59

[40] A new model for the three-dimensional folding of Escherichia coli 16 S ribosomal RNA .1. Fitting the RNA to a 3D electron microscopic map at 20 angstrom [J].

Mueller, F ;

Brimacombe, R .

JOURNAL OF MOLECULAR BIOLOGY, 1997, 271 (04) :524-544

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