Geometric and electronic control of thermal bergman cyclization

被引：90

作者：

Rawat, DS ^{[1
]}

Zaleski, JM ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA

来源：

SYNLETT | 2004年 / 03期

关键词：

enediyne; Bergman cyclization; metalloenediynes;

D O I：

10.1055/s-2004-815422

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The geometric and electronic contributions to Bergman cyclization of simple enediynes are compared and contrasted to those of recently developed metalloenediyne analogues. The comparison reveals that metals can have more diverse, subtle, and in some cases, more dramatic geometric effects upon Bergman cyclization than simple substitution chemistry. In addition to geometric consequences imposed by metals, electronic control of metalloenediyne cyclization is emerging as a complementary parameter in complex design.

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收藏

页码：393 / 421

页数：29

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