Antiproliferative activity of Citrus juices and HPLC evaluation of their flavonoid composition

被引：50

作者：

Camarda, Lorenzo

Di Stefano, Vita

Del Bosco, Sergio Fatta

Schillaci, Domenico

机构：

[1] Univ Palermo, Dipartimento Chim & Tecnol Farmaceut, I-90123 Palermo, Italy

[2] CNR, Ist Genet Vegetale, Palermo, Italy

来源：

FITOTERAPIA | 2007年 / 78卷 / 06期

关键词：

antiproliferative activity; Citrus species; flavanones;

D O I：

10.1016/j.fitote.2007.02.020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C clementina cv. Nules, C. aurantium subsp. myrtifolia, was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis. (C) 2007 Published by Elsevier B.V.

引用

页码：426 / 429

页数：4

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