Regulation of cytosolic enzymes in primary metabolism by reversible protein phosphorylation

被引：47

作者：

MacKintosh, C ^{[1
]}

机构：

[1] Univ Dundee, Dept Biochem, MRC, Prot Phosphorylat Unit, Dundee DD1 4HN, Scotland

来源：

CURRENT OPINION IN PLANT BIOLOGY | 1998年 / 1卷 / 03期

关键词：

D O I：

10.1016/S1369-5266(98)80108-8

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Recent discoveries have revealed that cytosolic enzymes of sugar, amino acid, and isoprenoid synthesis, sucrose breakdown and the plasma membrane H+-ATPase are regulated by reversible protein (serine/threonine) phosphorylation. In some cases, phosphorylation creates a phosphopeptide motif that is recognized by and binds to 14-3-3 proteins, and 14-3-3 binding changes the activity of the enzyme or ion pump. Intriguing new clues hint at how these cytosolic regulatory networks might link to signalling pathways triggered by hormones, nutrients, stresses, circadian rhythms, and other factors that regulate the growth and development of the whole plant.

引用

页码：224 / 229

页数：6

共 37 条

[1] Mechanism of activation and function of protein kinase B [J].

Alessi, DR ;

Cohen, P .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1998, 8 (01) :55-62

[2] The inhibitor protein of phosphorylated nitrate reductase from spinach (Spinacia oleracea) leaves is a 14-3-3 protein [J].

Bachmann, M ;

Huber, JL ;

Liao, PC ;

Gage, DA ;

Huber, SC .

FEBS LETTERS, 1996, 387 (2-3) :127-131

[3] 14-3-3 proteins associate with the regulatory phosphorylation site of spinach leaf nitrate reductase in an isoform-specific manner and reduce dephosphorylation of Ser-543 by endogenous protein phosphatases [J].

Bachmann, M ;

Huber, JL ;

Athwal, GS ;

Wu, K ;

Ferl, RJ ;

Huber, SC .

FEBS LETTERS, 1996, 398 (01) :26-30

[4] The 14-3-3 proteins associate with the plant plasma membrane H+-ATPase to generate a fusicoccin binding complex and a fusicoccin responsive system [J].

Baunsgaard, L ;

Fuglsang, AT ;

Jahn, T ;

Korthout, HAAJ ;

de Boer, AH ;

Palmgren, MG .

PLANT JOURNAL, 1998, 13 (05) :661-671

[5] Localization of 14-3-3 proteins in the nuclei of arabidopsis and maize [J].

Bihn, EA ;

Paul, AL ;

Wang, SW ;

Erdos, GW ;

Ferl, RJ .

PLANT JOURNAL, 1997, 12 (06) :1439-1445

[6] Isolation and molecular characterization of the Arabidopsis TPS1 gene, encoding trehalose-6-phosphate synthase [J].

Blázquez, MA ;

Santos, E ;

Flores, CL ;

Martínez-Zapater, JM ;

Salinas, J ;

Gancedo, C .

PLANT JOURNAL, 1998, 13 (05) :685-689

[7] Interaction of the maize and Arabidopsis kinase interaction domains with a subset of receptor-like protein kinases: Implications for transmembrane signaling in plants [J].

Braun, DM ;

Stone, JM ;

Walker, JC .

PLANT JOURNAL, 1997, 12 (01) :83-95

[8] SIMILAR SUBSTRATE RECOGNITION MOTIFS FOR MAMMALIAN AMP-ACTIVATED PROTEIN-KINASE, HIGHER-PLANT HMG-COA REDUCTASE KINASE-A, YEAST SNF1, AND MAMMALIAN CALMODULIN-DEPENDENT PROTEIN-KINASE-I [J].

DALE, S ;

WILSON, WA ;

EDELMAN, AM ;

HARDIE, DG .

FEBS LETTERS, 1995, 361 (2-3) :191-195

[9] The major form of ADP-glucose pyrophosphorylase in maize endosperm is extra-plastidial [J].

Denyer, K ;

Dunlap, F ;

Thorbjornsen, T ;

Keeling, P ;

Smith, AM .

PLANT PHYSIOLOGY, 1996, 112 (02) :779-785

[10] Dephosphorylation activates the purified plant plasma membrane H+-ATPase -: Possible function of phosphothreonine residues in a mechanism not involving the regulatory C-terminal domain of the enzyme [J].

Desbrosses, G ;

Stelling, J ;

Renaudin, JP .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 251 (1-2) :496-503

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