Good to CU

被引：21

作者：

Gu, YP ^{[1
]}

Sundquist, WI ^{[1
]}

机构：

[1] Univ Utah, Dept Biochem, Salt Lake City, UT 84132 USA

来源：

NATURE | 2003年 / 424卷 / 6944期

关键词：

D O I：

10.1038/424021a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A powerful arm of the cellular defence against microbial invaders has been characterized. APOBEC3G, a protein that can fight off HIV, works by introducing 'typographical errors' during viral replication.

引用

页码：21 / 22

页数：2

共 18 条

[11] Initial sequencing and analysis of the human genome
Lander, ES
Int Human Genome Sequencing Consortium
Linton, LM
Birren, B
Nusbaum, C
Zody, MC
Baldwin, J
Devon, K
Dewar, K
Doyle, M
FitzHugh, W
Funke, R
Gage, D
Harris, K
Heaford, A
Howland, J
Kann, L
Lehoczky, J
LeVine, R
McEwan, P
McKernan, K
Meldrim, J
Mesirov, JP
Miranda, C
Morris, W
Naylor, J
Raymond, C
Rosetti, M
Santos, R
Sheridan, A
Sougnez, C
Stange-Thomann, N
Stojanovic, N
Subramanian, A
Wyman, D
Rogers, J
Sulston, J
Ainscough, R
Beck, S
Bentley, D
Burton, J
Clee, C
Carter, N
Coulson, A
Deadman, R
Deloukas, P
Dunham, A
Dunham, I
Durbin, R
French, L
[J]. NATURE, 2001, 409 (6822) : 860 - 921
[12] Hypermutation of HIV-1 DNA in the absence of the Vif protein
Lecossier, D
Bouchonnet, F
Clavel, F
Hance, AJ
[J]. SCIENCE, 2003, 300 (5622) : 1112 - 1112
[13] Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
Mangeat, B
Turelli, P
Caron, G
Friedli, M
Perrin, L
Trono, D
[J]. NATURE, 2003, 424 (6944) : 99 - 103
[14] Apobec-1 interacts with a 65-kDa complementing protein to edit apolipoprotein-B mRNA in vitro
Mehta, A
Banerjee, S
Driscoll, DM
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (45) : 28294 - 28299
[15] Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
Sheehy, AM
Gaddis, NC
Choi, JD
Malim, MH
[J]. NATURE, 2002, 418 (6898) : 646 - 650
[16] THE HIV A (SOR) GENE-PRODUCT IS ESSENTIAL FOR VIRUS INFECTIVITY
STREBEL, K
DAUGHERTY, D
CLOUSE, K
COHEN, D
FOLKS, T
MARTIN, MA
[J]. NATURE, 1987, 328 (6132) : 728 - 730
[17] VIF IS CRUCIAL FOR HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROVIRAL DNA-SYNTHESIS IN INFECTED-CELLS
VONSCHWEDLER, U
SONG, JP
AIKEN, C
TRONO, D
[J]. JOURNAL OF VIROLOGY, 1993, 67 (08) : 4945 - 4955
[18] The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
Zhang, H
Yang, B
Pomerantz, RJ
Zhang, CM
Arunachalam, SC
Gao, L
[J]. NATURE, 2003, 424 (6944) : 94 - 98

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