Adjuvants and their signaling pathways: beyond TLRs

被引：19

作者：

Lien, E ^{[1
]}

Golenbock, DT ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Div Infect Dis & Immunol, Worcester, MA 01605 USA

来源：

NATURE IMMUNOLOGY | 2003年 / 4卷 / 12期

关键词：

D O I：

10.1038/ni1203-1162

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

TLR ligands mediate adjuvant effects. Unlike lipopolysaccharide, poly(I:C) is capable of using a TLR-Trif-independent pathway to induce costimulatory molecule upregulation on antigen-presenting cells.

引用

页码：1162 / 1164

页数：4

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