Radical trifluoromethylation of titanium ate enolate

被引：83

作者：

Itoh, Y ^{[1
]}

Mikami, K ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Appl Chem, Tokyo 1528552, Japan

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 04期

关键词：

D O I：

10.1021/ol047565a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The radical trifluoromethylation of ketone titanium ate enolates gave alpha-CF3 ketones in good yields. The use of excess amount of LDA and Ti((OPr)-Pr-i)(4) in the preparation of titanium ate enolates is the key to the efficient radical trifluoromethylation.

引用

页码：649 / 651

页数：3

共 45 条

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