The microbiological hydroxylation of some steroids with a cortical side chain by Cephalosporium aphidicola

被引:7
作者
Hanson, JR [1 ]
Hunter, AC [1 ]
机构
[1] Univ Sussex, Sch Chem Phys & Environm Sci, Brighton BN1 9QJ, E Sussex, England
关键词
Cephalosporium aphidicola; hyphomycetes; microbiological hydroxylation; steroid; 21-hydroxypregna-4-en-3,20-dione;
D O I
10.1016/S0031-9422(98)00327-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hydroxylation of pregna-4-en-3-ones at C-11 alpha by the fungus Cephalosporium aphidicola is shown to be affected by the nature of the pregnane side chain whilst hydroxylation at C-6 beta is unaffected. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2359 / 2362
页数:4
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