The amyloid cascade hypothesis

被引：96

作者：

Korczyn, Amos D. ^{[1
]}

机构：

[1] Tel Aviv Univ, Sackler Sch Med, Sieratzki Chair Neurol, IL-69978 Tel Aviv, Israel

来源：

ALZHEIMERS & DEMENTIA | 2008年 / 4卷 / 03期

关键词：

D O I：

10.1016/j.jalz.2007.11.008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The amyloid deposits in the brains of patients with Alzheimer's disease have attracted attention and are now considered not only an essential requirement for pathological diagnosis but also an important clue to the pathogenesis of the disease. This article looks critically at the basis of the "amyloid cascade hypothesis" to conclude that there are many issues that need to be resolved since they are inconsistent with the hypothesis. (C) 2008 The Alzheimer's Association. All rights reserved.

引用

页码：176 / 178

页数：3

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