Chitosan-N-poly(ethylene glycol) brush copolymers:: Synthesis and adsorption on silica surface

被引：40

作者：

Gorochovceva, N ^{[1
]}

Naderi, A

Dedinaite, A

Makuska, R

机构：

[1] Vilnius State Univ, Dept Polymer Chem, LT-03225 Vilnius, Lithuania

[2] Royal Inst Technol, Dept Chem Surface Chem, SE-10044 Stockholm, Sweden

来源：

EUROPEAN POLYMER JOURNAL | 2005年 / 41卷 / 11期

关键词：

chitosan; poly(ethylene glycol); water-soluble; graft copolymer; reductive amination; adsorption; QCM-D; reflectometry;

D O I：

10.1016/j.eurpolymj.2005.05.021

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Chitosan-N-poly(ethylene glycol) brush copolymers with different degree of substitution (DS) were synthesized via reductive amination of chitosan by rnethoxy poly(ethylene glycol) (MPEG) aldehyde. Chitosan-N-MPEG copolymers were high-molecular-weight products with desirable DS; solubility and solution viscosity of those copolymers depended on the method of the synthesis of MPEG aldehyde and on DS. Synthesis of MPEG aldehyde by the use of TEMPO radical/BAIB was not suitable because of partial oxidation of methoxy groups of MPEG resulting in bifunctional PEG derivatives leading to cross-linking. Adsorption studies of chitosan-N-MPEG graft copolymers oil silica surface show that these polymers adsorb in highly hydrated layers. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2653 / 2662

页数：10

共 29 条

[1]

ANELLI PL, 1987, J ORG CHEM, V52, P2559

[2] A SIMPLE SPECTROPHOTOMETRIC DETERMINATION OF FORMALDEHYDE AND OTHER ALDEHYDES - APPLICATION TO PERIODATE-OXIDIZED GLYCOL SYSTEMS [J].

AVIGAD, G .

ANALYTICAL BIOCHEMISTRY, 1983, 134 (02) :499-504

[3] Reductive amination using poly(ethylene glycol) acetaldehyde hydrate generated in situ: Applications to chitosan and lysozyme [J].

Bentley, MD ;

Roberts, MJ ;

Harris, JM .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1998, 87 (11) :1446-1449

[4] Preparation and characterization of poly(ethylene glycol)-crosslinked reacetylated chitosans [J].

Dal Pozzo, A ;

Vanini, L ;

Fagnoni, M ;

Guerrini, M ;

De Benedittis, A ;

Muzzarelli, RAA .

CARBOHYDRATE POLYMERS, 2000, 42 (02) :201-206

[5]

DAVIS SS, Patent No. 6730735

[6] Alcohol oxidase from the yeast Pichia pastoris -: a potential catalyst for organic synthesis [J].

Dienys, G ;

Jarmalavicius, S ;

Budriene, S ;

Citavicius, D ;

Sereikaite, J .

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2003, 21 (1-2) :47-49

[7] REFLECTOMETRY AS A TOOL FOR ADSORPTION STUDIES [J].

DIJT, JC ;

STUART, MAC ;

FLEER, GJ .

ADVANCES IN COLLOID AND INTERFACE SCIENCE, 1994, 50 :79-101

[8] Synthesis and study of water-soluble chitosan-O-poly(ethylene glycol) graft copolymers [J].

Gorochovceva, N ;

Makuska, R .

EUROPEAN POLYMER JOURNAL, 2004, 40 (04) :685-691

[9]

GOROCHOVCEVA N, 2002, P BALT POL S 2002 VI, P172

[10]

GOROCHOVCEVA N, 2003, CHEM LISTY, V97, P433

← 1 2 3 →