RNA localization and the development of asymmetry during Drosophila oogenesis

被引：63

作者：

Grunert, S ^{[1
]}

StJohnston, D ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT GENET,CAMBRIDGE CB2 1QR,ENGLAND

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0959-437X(96)80059-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent work on axis formation in Drosophila has revealed that polarity arises in several distinct stages during oogenesis. One cell of a germline cyst is selected to become the oocyte, the position of the oocyte determines the posterior of the follicle, and the position of the oocyte nucleus determines the dorsal side. Each of these symmetry-breaking steps involves the asymmetric localization of a unique structure, leading to polarization of the cytoskeleton and the localization of specific mRNAs.

引用

页码：395 / 402

页数：8

共 59 条

[41] THE DROSOPHILA EGF RECEPTOR HOMOLOG (DER) GENE IS ALLELIC TO FAINT-LITTLE-BALL, A LOCUS ESSENTIAL FOR EMBRYONIC-DEVELOPMENT [J].