Electrolytic partial fluorination of organic compounds. 55. Highly regio- and stereoselective anodic monofluorination of 2,3-dihydrochroman-4-one and chromone derivatives

被引：30

作者：

Dawood, KM

Fuchigami, T

机构：

[1] Tokyo Inst Technol, Dept Elect Chem, Midori Ku, Yokohama, Kanagawa 2268502, Japan

[2] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 23期

关键词：

D O I：

10.1021/jo0105437

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Anodic monofluorination at the position a to the oxygen atom of the (E)-3-benzylidene-2,3-dihydrochroman-4-one derivatives was successfully carried out to provide the corresponding 2-fluorochromanones selectively. This is the first regioselective electrochemical fluorination of fused-type, oxygen-containing heterocyclic compounds. Anodic fluorination of a chromone derivative also gave a similar fluorinated chromanone stereoselectively.

引用

页码：7691 / 7695

页数：5

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