Hepatitis E vaccine

被引:31
作者
Aggarwal, Rakesh [2 ]
Jameel, Shahid [1 ]
机构
[1] Int Ctr Genet Engn & Biotechnol, Virol Grp, New Delhi 110067, India
[2] Sanjay Gandhi Postgrad Inst Med Sci, Dept Gastroenterol, Lucknow 226014, Uttar Pradesh, India
关键词
hepatitis; hepatitis E; HEV; vaccine;
D O I
10.1007/s12072-008-9071-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hepatitis E is an emerging disease in resource-poor regions of the world. It is estimated that about 2 billion people live in areas endemic for this disease. The inability to reproducibly culture hepatitis E virus makes it impossible to develop traditional live or inactivated vaccines. However, significant progress has been made in developing and testing recombinant subunit vaccines based on the viral capsid protein. This review summarizes these efforts.
引用
收藏
页码:308 / 315
页数:8
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