The pathophysiology of diarrhea

被引:25
作者
Sellin, JH [1 ]
机构
[1] Univ Texas, Sch Med, Div Gastroenterol, Houston, TX 77030 USA
关键词
diarrhea; transplantation; immunosuppression; GI complications;
D O I
10.1111/j.1399-0012.2001.00002.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Diarrhea is a very common event after transplantation, but its cause may be difficult to identify. The first step in determining the cause in any particular case is an understanding of the etiology of diarrhea in general. Although diarrhea often is categorized into such types as secretory versus osmotic, or electrolyte transport-related versus motility related, a thorough understanding of the problem requires knowledge of how the paracrine, immune, nervous and endocrine systems react to each other as well as to infection. drugs or other stimuli.
引用
收藏
页码:2 / 10
页数:9
相关论文
共 8 条
[1]   Short chain fatty acid rectal irrigation for left-sided ulcerative colitis: A randomised, placebo controlled trial [J].
Breuer, RI ;
Soergel, KH ;
Lashner, BA ;
Christ, ML ;
Hanauer, SB ;
Vanagunas, A ;
Harig, JM ;
Keshavarzian, A ;
Robinson, M ;
Sellin, JH ;
Weinberg, D ;
Vidican, DE ;
Flemal, KL ;
Rademaker, AW .
GUT, 1997, 40 (04) :485-491
[2]  
Cook SI, 1998, ALIMENT PHARM THER, V12, P499, DOI 10.1046/j.1365-2036.1998.00337.x
[3]   NEUROIMMUNE SIGNALING IN REGULATION OF INTESTINAL ION-TRANSPORT [J].
COOKE, HJ .
AMERICAN JOURNAL OF PHYSIOLOGY, 1994, 266 (02) :G167-G178
[4]  
FORDTRAN JS, 1986, CLIN GASTROENTEROL, V15, P477
[5]   Cytokines and the gut [J].
McAlindon, ME ;
Mahida, YR .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 1997, 9 (11) :1045-1050
[6]   Intravenous mycophenolate mofetil: safety, tolerability, and pharmacokinetics [J].
Pescovitz, MD ;
Conti, D ;
Dunn, J ;
Gonwa, T ;
Halloran, P ;
Sollinger, H ;
Tomlanovich, S ;
Weinstein, S ;
Inokuchi, S ;
Kiberd, B ;
Kittur, D ;
Merion, RM ;
Norman, D ;
Shoker, A ;
Wilburn, R ;
Nicholls, AJ ;
Arterburn, S ;
Dumont, E .
CLINICAL TRANSPLANTATION, 2000, 14 (03) :179-188
[7]   SEGMENTAL DIFFERENCES IN SHORT-CHAIN FATTY-ACID TRANSPORT IN RABBIT COLON - EFFECT OF PH AND NA [J].
SELLIN, JH ;
DESOIGNIE, R ;
BURLINGAME, S .
JOURNAL OF MEMBRANE BIOLOGY, 1993, 136 (02) :147-158
[8]   Short-chain fatty acids have polarized effects on sodium transport and intracellular pH in rabbit proximal colon [J].
Sellin, JH ;
De Soignie, R .
GASTROENTEROLOGY, 1998, 114 (04) :737-747