Exercise-induced asthma, respiratory and allergic disorders in elite athletes:: epidemiology, mechanisms and diagnosis:: Part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA2LEN

被引:257
作者
Carlsen, K. H. [1 ,2 ]
Anderson, S. D. [3 ]
Bjermer, L. [4 ]
Bonini, S. [5 ,6 ]
Brusasco, V. [7 ]
Canonica, W. [8 ]
Cummiskey, J. [9 ]
Delgado, L. [10 ]
Del Giacco, S. R. [11 ]
Drobnic, F. [12 ]
Haahtela, T. [13 ]
Larsson, K.
Palange, P. [14 ]
Popov, T. [15 ]
van Cauwenberge, P. [16 ]
机构
[1] Univ Oslo, Rikshosp, Fac Med, Dept Paediat,Med Ctr, NO-0791 Oslo, Norway
[2] Norwegian Sch Sport Sci, Oslo, Norway
[3] Royal Prince Alfred Hosp, Dept Resp Med, Camperdown, NSW 2050, Australia
[4] Univ Lund Hosp, Dept Resp Med & Allergol, S-22185 Lund, Sweden
[5] CNR, Inst Neurobiol & Mol Med, Rome, Italy
[6] Univ Naples 2, Naples, Italy
[7] Univ Genoa, Dipartimento Med Interna, Genoa, Italy
[8] Univ Genoa, Dept Internal Med, I-16126 Genoa, Italy
[9] Blackrock Clin, Dublin, Ireland
[10] Univ Porto, Serv & Lab Imunol, Fac Med, Hosp S Joao, P-4100 Oporto, Portugal
[11] Policlin Univ Cagliari, Cagliari, Italy
[12] Olymp Training Ctr CAR, Sports & Physiol Dept, Barcelona, Spain
[13] Univ Helsinki, Cent Hosp, Dept Allergy, Skin Allergy Hosp, Helsinki, Finland
[14] Dipartimento Med Clin, Rome, Italy
[15] Med Univ 1, Clin Ctr Allergol, Sofia, Bulgaria
[16] Univ Ghent, Dept Otorhinolaryngol, B-9000 Ghent, Belgium
关键词
asthma; allergy; bronchial responsiveness; sports; exercise-induced asthma;
D O I
10.1111/j.1398-9995.2008.01662.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Aims: To analyze the changes in the prevalence of asthma, bronchial hyperresponsiveness (BHR) and allergies in elite athletes over the past years, to review the specific pathogenetic features of these conditions and to make recommendations for their diagnosis. Mehtods: The Task Force reviewed present literature by searching Medline up to November 2006 for relevant papers by the search words: asthma, bronchial responsiveness, EIB, athletes and sports. Sign criteria were used to assess level of evidence and grades of recommendation. Results: The problems of sports-related asthma and allergy are outlined. Epidemiological evidence for an increased prevalence of asthma and BHR among competitive athletes, especially in endurance sports, is provided. The mechanisms for development of asthma and bronchial hyperresponsiveness in athletes are outlined. Criteria are given for the diagnosis of asthma and exercise induced asthma in the athlete. Conclusions: The prevalence of asthma and bronchial hyperresponsiveness is markedly increased in athletes, especially within endurance sports. Environmental factors often contribute. Recommendations for the diagnosis of asthma in athletes are outlined.
引用
收藏
页码:387 / 403
页数:17
相关论文
共 144 条
[51]   AIR-FLOW-INDUCED BRONCHOSPASM - IMBALANCE BETWEEN AIRWAY COOLING AND AIRWAY DRYING [J].
FREED, AN ;
KELLY, LJ ;
MENKES, HA .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1987, 136 (03) :595-599
[52]   DRY AIR-INDUCED MUCOSAL CELL INJURY AND BRONCHOVASCULAR LEAKAGE IN CANINE PERIPHERAL AIRWAYS [J].
FREED, AN ;
OMORI, C ;
SCHOFIELD, BH ;
MITZNER, W .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1994, 11 (06) :724-732
[53]   Exercise-induced anaphylaxis to wheat flour [J].
Gall, H ;
Steinert, M ;
Peter, RU .
ALLERGY, 2000, 55 (11) :1096-1097
[54]   AIRWAY COOLING AND REWARMING - THE 2ND REACTION SEQUENCE IN EXERCISE-INDUCED ASTHMA [J].
GILBERT, IA ;
MCFADDEN, ER .
JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (03) :699-704
[55]   EXERCISE BUT NOT METHACHOLINE DIFFERENTIATES ASTHMA FROM CHRONIC LUNG-DISEASE IN CHILDREN [J].
GODFREY, S ;
SPRINGER, C ;
NOVISKI, N ;
MAAYAN, C ;
AVITAL, A .
THORAX, 1991, 46 (07) :488-492
[56]   AN EXERCISE CHALLENGE PROTOCOL FOR EPIDEMIOLOGIC STUDIES OF ASTHMA IN CHILDREN - COMPARISON WITH HISTAMINE CHALLENGE [J].
HABY, MM ;
ANDERSON, SD ;
PEAT, JK ;
MELLIS, CM ;
TOELLE, BG ;
WOOLCOCK, AJ .
EUROPEAN RESPIRATORY JOURNAL, 1994, 7 (01) :43-49
[57]   Airway immunopathology of asthma with exercise-induced bronchoconstriction [J].
Hallstrand, TS ;
Moody, MW ;
Aitken, ML ;
Henderson, WR .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 116 (03) :586-593
[58]   Inflammatory basis of exercise-induced bronchoconstriction [J].
Hallstrand, TS ;
Moody, MW ;
Wurfel, MM ;
Schwartz, LB ;
Henderson, WR ;
Aitken, ML .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 172 (06) :679-686
[59]   A new system for grading recommendations in evidence based guidelines [J].
Harbour, R ;
Miller, J .
BRITISH MEDICAL JOURNAL, 2001, 323 (7308) :334-336
[60]   BRONCHIAL RESPONSIVENESS TO HISTAMINE OR METHACHOLINE IN ASTHMA - MEASUREMENT AND CLINICAL-SIGNIFICANCE [J].
HARGREAVE, FE ;
RYAN, G ;
THOMSON, NC ;
OBYRNE, PM ;
LATIMER, K ;
JUNIPER, EF ;
DOLOVICH, J .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1981, 68 (05) :347-355